首页 Sangamo BioSciences(usSGMO)-基本信息

Sangamo BioSciences(usSGMO)-基本信息

日报更新时间:

周报更新时间:04-11 03:39

行情信息

今开价:11.83

最高价:11.85

成交量:580741.0

昨收价:11.77

最低价:11.33

最新价:11.485

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概要信息

英文名称:Sangamo BioSciences


行业:医疗


简介:Sangamo Therapeutics, Inc.是于1995年6月22日在特拉华州注册成立,专注于为基因调控和基因修饰的新型转录因子的开发和商业化


电话:1-510-9706000


最新量化综合结论
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Sangamo Therapeutics公司专注于研究、开发、并为治疗基因组编译和基因调控工程DNA结合蛋白的商业化。Sangamo Therapeutics产品包括: 专利技术的——锌指DNA结合蛋白(zinc finger DNA-binding protein,ZFP)技术用于特定的基因组修饰和基因调控。该ZFPs 也可以连接到一个限制性内切酶的切割结构域以创建锌指核酸酶(ZFN),其可用于通过添加或敲除特定基因特异性修饰DNA 序列的蛋白质;和ZFP转录因子(ZFP TFS),可用于打开基因或关闭的蛋白质。 SB-728-T——用于人类免疫缺陷病毒和爱滋病毒/爱滋病的ZFN介导的自体T细胞产品,其产品处于II期及I期临床试验阶段。 SB-728-HSPC——目前处于治疗爱滋病毒/爱滋病的I/II期临床试验阶段。 Sangamo Therapeutics公司还从事血友病B、血友病A、第一型黏多糖症(MPS)和溶小体储积症(LSD)MPS II的ZFP治疗学的体内基因组编辑应用I/II期研究;其他LSD的专利临床前计划,以及和某些中枢神经系统疾病与癌症免疫治疗的研究阶段性计划。Sangamo Therapeutics与Biogen Inc.有合作伙伴关系,开发血红蛋白病的治疗性基因组编辑产品;与Shire International GmbH合作,开发亨廷顿氏病(Huntington's disease)的临床前开发项目;与Sigma-Aldrich Corporation签署有许可协议,开发基于ZFP的实验室研究试剂;与Dow AgroSciences, LLC签署许可协议,修饰植物细胞,植物或植物细胞培养物的基因组或改变蛋白质表达。

交易日期 交易人 职位 类型 交易份额 价格
2019-06-09 Zakrzewski (Joseph S. JR) Director Buy 2500 --
2019-06-09 Carey (Robert F.) Director Buy 2500 --
2019-06-09 Smith (Karen L) Director Buy 2500 --
2019-06-09 Dilly (Stephen G. M.D. Ph.D.) Director Buy 2500 --
2019-06-09 Ramasastry Saira Director Buy 2500 --
2019-06-09 Parker (H Stewart) Director Buy 2500 --
2019-05-14 Yi (Kathy Y) Chief Financial Officer Buy 5000 4.55
2019-05-14 Yi (Kathy Y) Chief Financial Officer Sell 5000 10.00
2019-04-14 Yi (Kathy Y) Chief Financial Officer Buy 5000 4.55
2019-04-14 Yi (Kathy Y) Chief Financial Officer Sell 5000 12.11
2019-03-14 Yi (Kathy Y) Chief Financial Officer Sell 5000 10.00
2019-03-14 Yi (Kathy Y) Chief Financial Officer Buy 5000 4.55
2019-02-28 Yi (Kathy Y) Chief Financial Officer Sell 5000 10.00
2019-02-28 Yi (Kathy Y) Chief Financial Officer Buy 5000 4.55
2019-02-24 Yi (Kathy Y) Chief Financial Officer Buy 19250 --
2019-02-24 Macrae (Sandy) Chief Executive Officer Buy 63250 --
2019-02-24 Turner (Heather D) General Counsel Buy 19250 --
2019-02-24 Boissel (Stephane) Officer Buy 17500 --
2019-01-23 Conner (Edward R) Officer Sell 834 11.10
2019-01-23 Yi (Kathy Y) Chief Financial Officer Sell 988 11.10
2019-01-14 Yi (Kathy Y) Chief Financial Officer Buy 5000 4.55
2019-01-14 Yi (Kathy Y) Chief Financial Officer Sell 5000 11.04
2019-01-06 Conner (Edward R) Officer Sell 5000 12.33
2019-01-06 Conner (Edward R) Officer Buy 5000 3.20
2018-12-16 Yi (Kathy Y) Chief Financial Officer Buy 5000 4.55

机构持股
持有者 持有份额 持股比例 份额变化 变化率 报告日期
Geode Capital Management, LLC 1252473 1.09% -1006257 -44.55% 2019-03-31
Vanguard Investments Australia Ltd 3356706 2.90% 1646 0.05% 2019-07-31
Bellevue Asset Management AG 3650000 3.16% 1000000 37.74% 2019-07-31
Wellington Management Company LLP 4313453 3.74% 2264728 110.54% 2019-03-31
BlackRock Fund Advisors 5094415 4.41% 70249 1.40% 2019-07-31
State Street Corporation 5852641 5.07% -57511 -0.97% 2019-03-31
Wasatch Advisors Inc. 6437908 5.58% 1359170 26.76% 2019-03-31
Vanguard Group Inc 7712588 6.69% 117336 1.54% 2019-03-31
BlackRock Inc 8334148 7.22% -96690 -1.15% 2019-03-31
SSGA Funds Management Inc 3083932 2.67% 46157 1.52% 2019-07-31
Fidelity SelectCo, LLC 2732503 2.36% -547235 -16.69% 2019-07-31
BB Biotech AG 2650000 2.30% 1300000 96.30% 2019-03-31
Northern Trust Investments N A 1322332 1.15% 821 0.06% 2019-03-31
Northern Trust Corp 1322332 1.15% 821 0.06% 2019-03-31
Dimensional Fund Advisors, Inc. 1516660 1.31% 277550 22.40% 2019-03-31
Dimensional Fund Advisors LP 1592576 1.38% 2476 0.16% 2019-07-31
Northern Trust Investments Inc 2061088 1.78% 65143 3.26% 2019-07-31
Credit Suisse First Boston (CSFB) 2346344 2.03% 1201 0.05% 2019-03-31
Fidelity Management and Research Company 2444750 2.12% -16400 -0.67% 2019-03-31
FMR Inc 2444750 2.12% -16400 -0.67% 2019-03-31
BlackRock Asset Management Canada Ltd 2356155 2.04% 192 0.01% 2019-05-31
Goldman Sachs Group Inc 1307020 1.28% 198005 17.85% 2018-12-31
Invesco Capital Management LLC 1241162 1.21% -251162 -16.83% 2019-03-31
Rhenman & Partners Asset Management AB 1167357 1.14% -- -- 2019-02-28
Casdin Capital, LLC 2000000 1.96% 600000 42.86% 2018-09-30
Teachers Advisors LLC 2000970 1.96% 1073749 115.80% 2018-09-30
Baker Bros Advisors LP 1283923 1.26% -- -- 2018-09-30
Adage Capital Partners Gp LLC 1400000 1.37% -1850000 -56.92% 2018-09-30
Rhenman Partners Asset Management AB 1197357 1.17% 145424 13.82% 2018-09-30
TIAA-CREF Investment Management LLC 1115652 1.09% 603346 117.77% 2018-09-30
BlackRock Institutional Trust Company NA 2850349 2.79% 467197 19.60% 2018-06-30
Fidelity Management & Research Company 1033555 1.01% 103358 11.11% 2018-11-30
Wells Fargo Advisors, LLC 707017 0.70% 288985 69.13% 2018-06-30
UBS Asset Mgmt Americas Inc 708179 0.70% 106100 17.62% 2018-06-30
UBS Group AG 676781 0.67% 676781 -- 2018-05-31
Alexandria Capital, LLC 897182 0.88% 15649 1.78% 2018-06-30
Teachers Advisors Inc 927221 0.91% 18434 2.03% 2018-06-30
NEXTHERA CAPITAL LP 1066914 1.05% 280538 35.67% 2018-06-30
EcoR1 Capital, LLC 1509671 1.49% 1509671 -- 2018-06-30
State Street Corp 6080644 5.98% 1543693 34.02% 2018-06-30
Deutsche Bank AG 620531 0.61% 349289 128.77% 2018-06-30
Invesco PowerShares Capital Mgmt LLC 718823 0.83% -184470 -20.42% 2018-03-31
Morgan Stanley & Co Inc 903661 1.04% 714771 378.41% 2018-03-31
Opaleye Management Inc 535000 0.61% -45000 -7.76% 2018-03-31
Tocqueville Asset Management L.P. 665890 0.78% 341075 105.01% 2017-12-31
Goldman Sachs Asset Management LP 762153 0.89% 286772 60.32% 2017-12-31
Bogle Investment Management L P 966128 1.13% -75350 -7.23% 2017-12-31
D. E. Shaw & Co LP 1364295 1.59% -240260 -14.97% 2017-12-31
Fic Capital Inc 909437 1.08% -50901 -5.30% 2017-09-30
Point72 Asset Management, L.P. 693300 0.82% 335595 93.82% 2017-09-30
Millennium Management LLC 942097 1.12% 465953 97.86% 2017-09-30
Adage Capital Advisors, LLC 4000000 5.56% 4000000 -- 2017-05-25
RA Capital Management, LLC 1250000 1.49% -- -- 2017-09-30
Granahan Investment Management Inc.. 465090 0.55% -241769 -34.20% 2017-09-30
Frontier Capital Management CO Inc 487788 0.58% -7240 -1.46% 2017-09-30
Altrinsic Global Advisors LLC 540000 0.64% -40000 -6.90% 2017-09-30
Deerfield Management Co 653000 0.78% -441305 -40.33% 2017-09-30
Goldman Sachs Asset Management, L.P. 1546881 2.20% 1546881 -- 2015-12-31
Cormorant Asset Management, LLC 1402331 1.99% -- -- 2016-09-30
ING Investment Management LLC 1355208 1.92% 173325 14.67% 2016-09-30
Numeric Investors LLC 1003313 1.42% 537790 115.52% 2016-09-30
Orbimed Advisors, LLC 831500 1.18% 831500 -- 2016-09-30
Close Finsbury Asset Management Limited 831500 1.18% -- -- 2016-10-31
Renaissance Technologies Corp 594500 0.84% 480300 420.58% 2016-09-30
FMR LLC 4099975 4.00% 63180615 0.10% 1999-11-30
BlackRock, Inc. 4891466 4.00% 75377491 0.10% 1999-11-30
The Goldman Sachs Group, Inc. 5131055 4.00% 79069558 0.10% 1999-11-30
共同基金持股
持有者 持有份额 持股比例 份额变化 变化率 报告日期
Wellington Global Health Care Equity 461434 0.40% 6290 1.38% 2019-03-31
SPDR 2991469 2.59% 46410 1.58% 2019-07-31
iShares Russell 2000 ETF 2542253 2.20% 40959 1.64% 2019-07-30
Vanguard Extended Market Index Fund 1580347 1.37% 6755 0.43% 2019-06-30
Vanguard Small Cap Index 1497220 1.30% 8694 0.58% 2019-06-30
Wasatch Small Cap Growth Fund 1288714 1.11% -- -- 2019-06-30
Wasatch Core Growth Fund 1202934 1.04% -- -- 2019-06-30
iShares Nasdaq Biotechnology ETF 1138802 0.99% 11792 1.05% 2019-07-30
Wasatch Ultra Growth Fund 931390 0.81% -- -- 2019-06-30
Vanguard Small Cap Growth Index Fund 845036 0.73% 2965 0.35% 2019-06-30
Rhenman Healthcare Eq L/S 843957 0.73% -- -- 2019-04-30
iShares Russell 2000 Growth ETF 745086 0.64% 8928 1.21% 2019-07-30
UBS (Lux) EF Biotech (USD) 649700 0.56% -- -- 2019-04-30
Fidelity 542744 0.47% -- -- 2019-06-30
DFA US Micro Cap Portfolio 539907 0.47% -- -- 2019-05-31
State Street Russell Small Cap 505856 0.44% 79400 18.62% 2019-07-31
State Street Russell Small/Mid Cap 469546 0.41% 35000 8.05% 2019-07-31
Vanguard Total Stock Market Index Fund 3334900 2.88% 1772 0.05% 2019-06-30
NT R2000 Growth Index Fund - Non-Lending 426752 0.37% -13500 -3.07% 2019-06-30
Wasatch Micro Cap Fund 478490 0.41% 153226 47.11% 2019-03-31
Invesco Dynamic Biotech & Genome ETF 782244 0.68% -- -- 2019-05-30
iShares US Small Cap ETF (CAD-Hedged) 2059918 1.79% -3456 -0.17% 2019-05-30
Vanguard Small Cap Index Fund 1474421 1.28% 154552 11.71% 2019-04-30
Wells Fargo Small Company Growth Fund 515314 0.45% 10519 2.08% 2019-02-28
Wells Fargo Small Co Gr Port 523593 0.45% 10274 2.00% 2019-02-28
Vanguard Explorer Fund 344267 0.34% -29389 -7.87% 2018-12-31
Wellington Global Healthcare Equity Fund 459759 0.45% 104154 29.29% 2018-12-31
CI Global Health Sciences Corporate Cl 310000 0.30% 50000 19.23% 2018-09-30
TIAA-CREF Quant Small-Cap Equity Fund 634400 0.62% -64600 -9.24% 2018-10-31
Handelsbanken America Small Cap 450000 0.44% -- -- 2018-10-31
Fidelity Advisor 491556 0.48% -271084 -35.55% 2018-07-31
iShares Nasdaq Biotechnology 1149846 0.90% -2190 -0.19% 2018-09-12
Wasatch Micro Cap 275924 0.27% 45196 19.59% 2018-06-30
Schwab US Small-Cap ETF 282432 0.22% -- -- 2018-09-13
Vanguard Market Neutral I 311452 0.31% -69678 -18.28% 2018-06-30
CREF Stock R1 418876 0.41% 38906 10.24% 2018-07-31
Wells Fargo Small Company Growth Admin 436125 0.43% 182 0.04% 2018-07-31
Vanguard Total Stock Mkt Idx 2577589 2.54% -- -- 2018-07-31
Vanguard Extended Market Idx Inv 1338838 1.32% 42600 3.29% 2018-07-31
Wasatch Small Cap Growth Investor 1195813 1.18% -15296 -1.26% 2018-06-30
iShares Russell 2000 Growth 970371 0.76% -936 -0.10% 2018-09-12
Wasatch Core Growth 721478 0.71% 164683 29.58% 2018-06-30
Vanguard Small Cap Growth Index Inv 729574 0.72% 9769 1.36% 2018-07-31
Vanguard Explorer Inv 628859 0.62% 269846 75.16% 2018-06-30
TIAA-CREF Small-Cap Equity Instl 633200 0.62% -- -- 2018-07-31
PowerShares Dynamic Biotech & Genome ETF 439020 0.35% -- -- 2018-09-13
Fidelity Spartan 466263 0.46% -- -- 2018-07-31
Northern Trust Russell 2000 Index Fund - DC - Non-Lending 247886 0.24% -624 -0.25% 2018-07-31
Vanguard Strategic Small-Cap Equity Inv 415969 0.48% 164940 65.71% 2018-03-31
Vanguard Strategic Equity Inv 191956 0.22% 191956 -- 2018-03-31
Federated MDT Small Cap Core A 239684 0.28% 69471 40.81% 2018-03-31
AST Prudential Growth Allocation Port 230500 0.26% -- -- 2018-03-31
Vanguard Health Care ETF 188300 0.22% 2599 1.40% 2018-02-28
American Century Small Company Inv 259194 0.30% 75498 41.10% 2017-12-31
iShares Micro-Cap 190700 0.22% -- -- 2018-03-21
PowerShares DWA Healthcare Momentum ETF 202324 0.22% -- -- 2018-03-22
Royce Value Trust 209315 0.25% -93500 -30.88% 2017-12-31
JNL Multi-Manager Small Cap Growth B 233619 0.28% -80300 -25.58% 2017-09-30
Goldman Sachs Small Cap Gr Insghts A 257727 0.31% 138285 115.78% 2017-10-31
Wasatch Ultra Growth 449297 0.64% 136362 43.58% 2016-12-31
Royce Micro Cap Trust 281785 0.40% 90000 46.93% 2016-12-31
Wasatch Global Opportunities Investor 173984 0.25% -52903 -23.32% 2016-12-31
Schwab Instl Small Cap Tr Fd-Instl 103354 0.15% 22707 28.16% 2016-09-30
SPDR® S&P Biotech ETF 2973910 4.30% 19432 0.70% 2015-11-19
iShares Russell 2000 (AU) 1099034 1.60% -1386 -0.10% 2015-11-19
Fidelity Advisor® Biotechnology Fund 682852 1.00% -- -- 2015-09-30
Dreyfus Opportunistic Small Cap Fund 532928 0.80% -37695 -6.60% 2015-09-30
Franklin Biotechnology Discovery 433400 0.60% -- -- 2015-07-31
Eventide Gilead Fund 384200 0.60% -- -- 2015-06-30
Fidelity® Select Biotechnology Portfolio 3556931 5.10% -- -- 2015-09-30
Voya SmallCap Opportunities Fund 339600 0.50% 106400 45.60% 2015-09-30

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