首页 彪马生物技术(usPBYI)-基本信息

彪马生物技术(usPBYI)-基本信息

日报更新时间:07-02 06:53

周报更新时间:01-16 11:49

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概要信息

中文名称:彪马生物技术


英文名称:Puma Biotechnology


简介:Puma Biotechnology, Inc.是于2007年4月27日成立的特拉华州公司,该公司是一家集开发阶段的生物制药公司,收购并开发创新的产品,致力于各种形式的癌症治疗


电话:1-424-2486500


最新量化综合结论
百科信息
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  • 百科
  • 员工交易记录
  • 持股信息

目前,Puma Biotechnology目前主要有3个候选药物: PB272 neratinib(口服),用于治疗早期乳腺癌,转移性乳腺癌,非小细胞肺癌,HER2突变阳性实体瘤和HER2突变的非扩增乳腺癌; PB272 neratinib(静脉注射); 公司还开发了PB357,这是一种口服药物,是一种不可逆的酪氨酸激酶抑制剂,通过表皮生长因子受体HER1,HER2和HER4阻断信号转导。彪马生物技术公司与辉瑞公司签订了许可协议,用于开发,生产和商业化PB272奈拉替尼(口服),PB272奈拉替尼(静脉注射),PB357和某些相关化合物。2017年7月,Puma Biotechnology旗下的试验性乳腺癌治疗药物获得了FDA批准,该药用于治疗拥有特定基因突变的早期乳腺癌患者。

交易日期 交易人 职位 类型 交易份额 价格
2016-10-13 Auerbach (Alan H) Chief Executive Officer Buy 150000 --
2016-10-13 Bryce (Richard Paul) Officer Buy 31500 --
2016-10-13 Charnas (Robert) Divisional Officer Buy 31500 --
2016-10-13 Eyler (Charles R) Officer and Treasurer Buy 10500 --
2016-10-13 Lo (Steven) Officer Buy 31500 --
2015-07-05 Bryce (Richard Paul) Officer Buy 3000 11.30
2015-07-05 Bryce (Richard Paul) Officer Sell 3000 110.03

机构持股
持有者 持有份额 持股比例 份额变化 变化率 报告日期
Macquarie Investment Management 772921 2.00% 58501 8.19% 2019-07-31
Sarissa Capital Management LP 1417000 3.67% 74000 5.51% 2019-03-31
State Street Corporation 1770445 4.59% -1089165 -38.09% 2019-03-31
Orbimed Advisors, LLC 1880000 4.87% -718883 -27.66% 2019-03-31
HHG PLC 2170423 5.62% 308479 16.57% 2019-03-31
BlackRock Inc 2503753 6.48% -162133 -6.08% 2019-03-31
Partner Fund Management LP 2603920 6.74% 2603920 -- 2019-03-31
Vanguard Group Inc 2946894 7.63% 152157 5.44% 2019-03-31
SSGA Funds Management Inc 4046371 10.48% 78730 1.98% 2019-07-31
BlackRock Fund Advisors 1375688 3.56% 6457 0.47% 2019-07-31
Federated Investors Inc 1297759 3.36% -231141 -15.12% 2019-03-31
Federated Equity Mgmt Co. Of Penn 1297759 3.36% -231141 -15.12% 2019-07-31
T. Rowe Price Associates, Inc. 785965 2.04% 785965 -- 2019-03-31
Delaware Management Company 835536 2.16% 21560 2.65% 2019-07-31
Great Point Partners LLC 900000 2.33% -479700 -34.77% 2019-03-31
Macquarie Group Ltd 987168 2.56% 161972 19.63% 2019-03-31
Vanguard Investments Australia Ltd 992792 2.57% 57 0.01% 2019-07-31
Millennium Management LLC 1078404 2.79% -254292 -19.08% 2019-03-31
Palo Alto Investors, LLC 1180780 3.06% 20880 1.80% 2019-03-31
Fred Alger Management Inc 1190675 3.08% 368634 44.84% 2019-03-31
Janus Capital Management LLC 1998434 5.18% -1723957 -46.31% 2019-06-30
Camber Capital Management LLC 1300000 3.38% 550000 73.33% 2018-12-31
Melqart Asset Management (UK) Ltd. 1159790 3.01% 756490 187.58% 2018-12-31
FMR Inc 860266 2.23% -521627 -37.75% 2018-12-31
Fidelity Management and Research Company 855866 2.22% -56887 -6.23% 2018-12-31
Citadel Advisors Llc 1124431 2.92% 316423 39.16% 2018-09-30
Fidelity SelectCo, LLC 867741 2.25% -464587 -34.87% 2019-03-31
Consonance Capital Management LP 2303455 6.04% 214338 10.26% 2018-09-30
venBio Select Advisor LLC 1150685 3.02% 116310 11.24% 2018-09-30
Point72 Asset Management, L.P. 764590 2.00% -155185 -16.87% 2018-09-30
D. E. Shaw & Co LP 792544 2.08% -582501 -42.36% 2018-06-30
BlackRock Institutional Trust Company NA 870611 2.28% 35001 4.19% 2018-06-30
Franklin Advisers, Inc. 749845 1.97% -106155 -12.40% 2018-06-30
Franklin Resources Inc 749845 1.97% -106155 -12.40% 2018-06-30
Redmile Group, LLC 1095612 2.87% 182039 19.93% 2018-03-31
Hartford Funds Management Company, LLC 839855 2.20% -259126 -23.58% 2018-10-31
Jennison Associates LLC 950998 2.49% 465453 95.86% 2018-06-30
Orbimed Capital LLC 1238846 3.30% 1238846 -- 2017-12-31
Schroder Investment Management North America Inc. 7155648 5.65% 6810683 1974.31% 2018-06-30
State Street Corp 1971243 5.20% 481475 32.32% 2018-06-30
Franklin Advisers Inc 749845 1.98% -106155 -12.40% 2018-06-30
Close Finsbury Asset Management Limited 818537 2.16% -113680 -12.19% 2018-05-31
Fidelity Institutional Asset Management 706084 1.86% 180005 34.22% 2018-06-30
Perceptive Advisors LLC 442179 1.17% -261641 -37.17% 2018-03-31
Tourbillon Capital Partners LP 421966 1.12% 421966 -- 2018-03-31
Rock Springs Capital Management LP 475800 1.26% 62900 15.23% 2018-06-30
Columbia Mangmt Investment Advisers, LLC 409867 1.09% 81971 25.00% 2018-03-31
NORGES BANK 716003 1.90% 323124 82.25% 2017-12-31
Polar Capital LLP 445000 1.18% 85000 23.61% 2017-12-31
Goldman, Sachs & Co. 478372 1.27% 4614 0.97% 2017-12-31
Adage Capital Partners Gp LLC 2222500 5.91% -327500 -12.84% 2017-12-31
PointState Capital LP 414010 1.11% -191350 -31.61% 2017-09-30
Emerald Advisers Inc 402668 1.07% 32633 8.82% 2017-12-31
Deutsche Bank AG 597524 1.60% 536025 871.60% 2017-09-30
Brookside Capital Management LLC 657876 1.76% 318882 94.07% 2017-09-30
Ascend Capital LLC 716717 1.92% 656662 1093.43% 2017-09-30
Wellington Management Company LLP 702894 2.16% 690271 5468.36% 2016-09-30
American Century Inv Mgt Inc 651675 2.00% 651675 -- 2016-09-30
Northern Trust Investments N A 275871 0.85% 3176 1.16% 2016-09-30
Weatherbie M A & Co Inc 262286 0.81% -18699 -6.65% 2016-09-30
Tekla Capital Management LLC 260200 0.80% -- -- 2016-09-30
Bellevue Asset Management AG 241991 0.75% -190000 -43.98% 2016-09-30
BB Biotech AG 241991 0.74% -190000 -43.98% 2016-09-30
Clough Capital Partners, LP 233100 0.72% -13500 -5.47% 2016-09-30
Capital Research Global Investors 1944740 4.00% 351181149 0.10% 1999-11-30
FMR LLC 4035436 4.00% 728719033 0.10% 1999-11-30
Alan. H. Auerbach 4040000 4.00% 729543200 0.10% 1999-11-30
Adage Capital Partners L.P 5686668 4.00% 1026898507 0.20% 1999-11-30
共同基金持股
持有者 持有份额 持股比例 份额变化 变化率 报告日期
Pictet Biopharmaceutical Mother 127600 0.33% 64000 100.63% 2019-04-15
iShares Russell 2000 ETF 671037 1.74% 1309 0.20% 2019-07-30
Worldwide Healthcare 706000 1.83% -- -- 2019-04-30
Delaware Sm-Cap Core Eq-UBS 772921 2.00% 58501 8.19% 2019-06-30
Delaware Small Cap Core Fund 772921 2.00% 21490 2.86% 2019-06-30
Federated Kaufmann Fund 828159 2.14% -171841 -17.18% 2019-03-31
Vanguard Small Cap Index 851517 2.21% 4968 0.59% 2019-06-30
Vanguard Total Stock Market Index Fund 986844 2.56% 91 0.01% 2019-06-30
SPDR 4018033 10.41% 78812 2.00% 2019-07-31
Vanguard Small Cap Growth Index Fund 484431 1.25% 1711 0.35% 2019-06-30
Federated Kaufmann Small Cap Fund 446600 1.16% -54400 -10.86% 2019-03-31
State Street Russell Small/Mid Cap 128066 0.33% -- -- 2019-06-30
Fidelity 144708 0.37% -- -- 2019-06-30
TIAA-CREF Quant Small-Cap Equity Fund 145500 0.38% -2300 -1.56% 2019-05-31
Candriam Eqs L Biotechnology 223200 0.58% -- -- 2019-06-30
iShares Russell 2000 Growth ETF 278827 0.72% -- -- 2019-07-30
Alger SMid Cap Focus Fund 364028 0.94% 15111 4.33% 2019-05-31
iShares Nasdaq Biotechnology ETF 384016 0.99% 6517 1.73% 2019-07-30
Vanguard Extended Market Index Fund 429209 1.11% 2085 0.49% 2019-06-30
Pictet-Biotech 188364 0.49% -778 -0.41% 2018-09-30
Janus Henderson Global Life Sciences Fd 235084 0.61% -- -- 2018-09-30
Janus Henderson Venture Fund 460612 1.19% 74733 19.37% 2019-03-31
Janus Henderson Triton Fund 1537822 3.98% 224837 17.12% 2019-03-31
iShares US Small Cap ETF (CAD-Hedged) 612630 1.59% -1026 -0.17% 2019-05-30
Vanguard Small Cap Index Fund 848889 2.20% 2376 0.28% 2019-04-30
Voya SmallCap Opportunities Fund 189199 0.49% 74848 65.45% 2018-12-31
Biotech Growth Trust Plc 178000 0.46% -58500 -24.74% 2018-11-30
HBM Healthcare Investments AG 205151 0.54% -- -- 2018-09-30
Polar Capital Healthcare Opps Fund 197862 0.52% -188267 -48.76% 2018-02-28
Janus Henderson Research Fund 914550 2.40% -231148 -20.18% 2018-06-30
Janus Henderson Enterprise Fund 744613 1.95% 53195 7.69% 2018-03-31
Carillon Eagle Small Cap Growth Fund 207820 0.54% -- -- 2018-06-30
Franklin Biotechnology Discovery Fund 263800 0.69% -8500 -3.12% 2018-09-30
T. Rowe Price New Horizons Fund 597044 1.57% -1264974 -67.94% 2017-12-31
T. Rowe Price Health Sciences Fund 634060 1.66% -1488269 -70.12% 2017-12-31
Hartford MidCap Fund 806035 2.11% -242906 -23.16% 2017-07-31
Prudential Jennison Small Company B 384820 1.02% 52664 15.86% 2018-07-31
Emerald Growth A 189099 0.50% -- -- 2018-07-31
Prudential Jennison Health Sciences A 204643 0.54% -- -- 2018-07-31
Janus Research D 914550 2.41% -231148 -20.18% 2018-06-30
Janus Triton D 795067 2.10% 129873 19.52% 2018-06-30
Vanguard Total Stock Mkt Idx 798376 2.11% 782 0.10% 2018-07-31
Janus Global Life Sciences D 445773 1.18% -64835 -12.70% 2018-06-30
Vanguard Small Cap Growth Index Inv 462544 1.22% 8074 1.78% 2018-07-31
iShares Nasdaq Biotechnology 429993 1.28% -819 -0.19% 2018-09-12
Vanguard Extended Market Idx Inv 404392 1.07% 3000 0.75% 2018-07-31
Delaware Small Cap Core A 370900 0.98% 24700 7.13% 2018-07-31
FIAM Small Company Pool 157600 0.42% 157600 -- 2018-03-31
Fidelity Advisor 226287 0.60% -- -- 2018-07-31
Eagle Small Cap Growth A 207820 0.55% -- -- 2018-06-30
Franklin Biotechnology Discovery A 282500 0.75% -- -- 2018-07-31
iShares Russell 2000 Growth 280254 0.83% -270 -0.10% 2018-09-12
Janus Venture D 242817 0.64% -- -- 2018-06-30
Janus Enterprise D 744613 1.97% 53195 7.69% 2018-03-31
State Street Russell Small/Mid Cap Idx Fd Cl I 95621 0.26% 5198 5.75% 2017-06-30
Fidelity Spartan 132836 0.35% -- -- 2018-04-30
Wells Fargo Discovery Admin 183100 0.48% -- -- 2018-03-31
T. Rowe Price Small-Cap Value 222200 0.59% -6700 -2.93% 2017-12-31
T. Rowe Price New Horizons 597044 1.59% -1264974 -67.94% 2017-12-31
T. Rowe Price Health Sciences 634060 1.69% -1488269 -70.12% 2017-12-31
T. Rowe Price Health Sciences Port II 122674 0.33% 35243 40.31% 2017-09-30
VALIC Company I Health Sciences 129101 0.35% -7600 -5.56% 2017-10-31
Hartford MidCap A 1387087 3.77% 12647 0.92% 2016-12-31
American Century Heritage Inv 513944 1.40% 147761 40.35% 2016-12-31
Hartford MidCap HLS IA 356089 0.97% -- -- 2016-12-31
American Century All Cap Growth Inv 117290 0.32% 42090 55.97% 2016-12-31
Fidelity® Select Health Care Portfolio 1228000 3.80% -- -- 2015-09-30
Fidelity® Select Biotechnology Portfolio 1218897 3.80% -- -- 2015-09-30
Fidelity® OTC Portfolio 946587 2.90% -- -- 2015-09-30
Franklin Biotechnology Discovery 514000 1.60% -15200 -2.90% 2015-07-31
Fidelity Advisor® Health Care Fund 342439 1.10% -- -- 2015-09-30
Fidelity Advisor® Biotechnology Fund 296445 0.90% -- -- 2015-09-30
SPDR® S&P Biotech ETF 229279 0.60% 1500 0.70% 2015-11-19
VA CollegeAmerica Growth Fund of America 1608000 5.00% -- -- 2015-09-30

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