日报更新时间：
周报更新时间：04-18 04:06
今开价：55.43
最高价：56.0
成交量：209976.0
昨收价：55.68
最低价：54.44
最新价：54.645
中文名称：Agios制药
英文名称：Agios Pharmaceuticals
简介：Agios制药公司于2007年8月7日在特拉华州注册成立，是一家生物制药公司，致力于癌症新陈代谢和先天性代谢异常领域的研究，以挽救患者的生命，并且公司在该领域处于领先地位
电话：1-617-6498600
Agios Pharmaceuticals, Inc.是一家专注于研发癌症、代谢及罕见代谢性遗传疾病治疗药物的生物制药公司，开发产品包括： AG-221——一种口服的异柠檬酸脱氢酶蛋白（IDH）2突变强效抑制剂，目前处于I/II期临床试验阶段；同时，处于恶性血液病治疗的III期临床试验阶段；同时处于治疗治疗实体瘤的I/II期临床试验阶段； AG-120——一种突变（IDH）1蛋白强效抑制剂，目前处于I期临床试验阶段；同时处于恶性血液病结合治疗的Ib期临床试验阶段；同时处于治疗治疗实体瘤的I期临床试验阶段； AG-881——一种泛IDH突变体抑制剂，处于恶性血液肿瘤和实体瘤治疗的I期临床试验阶段； AG-348——一个强有力的激活剂，处于DRIVER PK II期临床试验阶段； AG-519——一种强活化剂，用于治疗患者的丙酮酸激酶缺乏症，目前处于I期临床试验阶段。Agios Pharmaceuticals, Inc.与Celgene Corporation签订了合作和授权协议，共同开发和商业化肿瘤治疗药物，并与Celgene International II Sarl合作，开发和商业化AG-881产品。
| 交易日期 | 交易人 | 职位 | 类型 | 交易份额 | 价格 |
|---|---|---|---|---|---|
| 2019-06-11 | Maraganore (John M) | Director | Gift | 5000 | -- |
| 2019-06-10 | Biller Scott | Officer | Buy | 7218 | 2.34 |
| 2019-05-30 | Maraganore (John M) | Director | Buy | 1400 | -- |
| 2019-05-30 | Ho (Maykin Ph.D.) | Director | Buy | 1400 | -- |
| 2019-05-30 | Fouse (Jacqualyn A.) | Chief Executive Officer | Buy | 1400 | -- |
| 2019-05-30 | Foster-Cheek (Kaye I) | Director | Buy | 1400 | -- |
| 2019-05-30 | Clark (Ian Thornton) | Director | Buy | 1400 | -- |
| 2019-05-30 | Clancy (Paul J.) | Director | Buy | 1400 | -- |
| 2019-05-30 | Scadden (David T M.D.) | Director | Buy | 1400 | -- |
| 2019-04-04 | Biller Scott | Officer | Sell | 599 | 68.12 |
| 2019-04-04 | Biller Scott | Officer | Sell | 2401 | 67.61 |
| 2019-04-04 | Biller Scott | Officer | Buy | 3000 | 39.76 |
| 2019-03-31 | Bowden (Christopher J M.D.) | Officer | Sell | 100 | 68.72 |
| 2019-03-31 | Bowden (Christopher J M.D.) | Officer | Sell | 5854 | 66.03 |
| 2019-03-31 | Bowden (Christopher J M.D.) | Officer | Sell | 2546 | 66.85 |
| 2019-03-31 | Bowden (Christopher J M.D.) | Officer | Buy | 10000 | 35.16 |
| 2019-03-31 | Bowden (Christopher J M.D.) | Officer | Sell | 1500 | 68.09 |
| 2019-03-14 | Bowden (Christopher J M.D.) | Officer | Sell | 1300 | 64.64 |
| 2019-03-14 | Bowden (Christopher J M.D.) | Officer | Buy | 10000 | 35.16 |
| 2019-03-14 | Bowden (Christopher J M.D.) | Officer | Sell | 8700 | 64.09 |
| 2019-03-04 | Biller Scott | Officer | Sell | 2600 | 67.73 |
| 2019-03-04 | Biller Scott | Officer | Buy | 2572 | 39.76 |
| 2019-03-04 | Biller Scott | Officer | Sell | 200 | 66.45 |
| 2019-03-04 | Biller Scott | Officer | Buy | 428 | 31.64 |
| 2019-03-04 | Biller Scott | Officer | Sell | 200 | 68.22 |
| 机构持股 | |||||
|---|---|---|---|---|---|
| 持有者 | 持有份额 | 持股比例 | 份额变化 | 变化率 | 报告日期 |
| BlackRock Fund Advisors | 1157385 | 1.97% | 5950 | 0.52% | 2019-07-31 |
| Bellevue Asset Management AG | 3138295 | 5.34% | 131861 | 4.39% | 2019-07-31 |
| Capital Research & Mgmt Co - Division 3 | 3247913 | 5.53% | 14744 | 0.46% | 2019-03-31 |
| BlackRock Inc | 3334365 | 5.68% | 9886 | 0.30% | 2019-03-31 |
| Vanguard Group Inc | 4646218 | 7.91% | 24269 | 0.53% | 2019-03-31 |
| Fidelity Management & Research Company | 5675388 | 9.66% | -617765 | -9.82% | 2019-07-31 |
| Wellington Management Company LLP | 8146943 | 13.88% | 3827 | 0.05% | 2019-03-31 |
| FMR Inc | 8759313 | 14.92% | 32512 | 0.37% | 2019-03-31 |
| Fidelity Management and Research Company | 8744713 | 14.89% | 32512 | 0.37% | 2019-03-31 |
| Capital Research and Management Company | 3132942 | 5.33% | -- | -- | 2019-07-31 |
| BB Biotech AG | 2978134 | 5.07% | 100000 | 3.47% | 2019-03-31 |
| T. Rowe Price Associates, Inc. | 2801812 | 4.77% | 449082 | 19.09% | 2019-03-31 |
| Fidelity SelectCo, LLC | 1315900 | 2.24% | -- | -- | 2019-07-31 |
| Vanguard Investments Australia Ltd | 1439494 | 2.45% | 176 | 0.01% | 2019-07-31 |
| ClearBridge Advisors, LLC | 1514658 | 2.58% | 10385 | 0.69% | 2019-03-31 |
| State Street Corporation | 1589571 | 2.71% | -56357 | -3.42% | 2019-03-31 |
| Goldman Sachs Group Inc | 1636073 | 2.79% | 320626 | 24.37% | 2019-03-31 |
| First Trust Advisors L.P. | 1774158 | 3.02% | 423931 | 31.40% | 2019-03-31 |
| Woodford Investment Management LLP | 2214459 | 3.77% | 237000 | 11.99% | 2019-03-31 |
| Fidelity Management Trust Co | 2331288 | 3.97% | 66388 | 2.93% | 2019-07-31 |
| Hartford Funds Management Company, LLC | 1514090 | 2.58% | -525629 | -25.77% | 2019-05-31 |
| Deutsche Asset Management Investment GmbH | 1383132 | 2.36% | 1036551 | 299.08% | 2019-05-31 |
| Legg Mason Partners Fund Advisor, LLC | 1105034 | 1.90% | -190 | -0.02% | 2018-12-31 |
| BlackRock Institutional Trust Company NA | 1355511 | 2.33% | -33176 | -2.39% | 2018-06-30 |
| Lord, Abbett & Co LLC | 1208083 | 2.08% | 163737 | 15.68% | 2018-06-30 |
| Partner Fund Management LP | 614506 | 1.06% | -62585 | -9.24% | 2018-06-30 |
| Celgene Corp | 6718433 | 11.79% | 851154 | 14.51% | 2018-01-23 |
| Invesco Advisers, Inc | 818464 | 1.41% | -9010 | -1.09% | 2018-06-30 |
| State Street Corp | 1348516 | 2.33% | -140992 | -9.47% | 2018-06-30 |
| Goldman, Sachs & Co. | 724308 | 1.25% | 96672 | 15.40% | 2018-06-30 |
| Alkeon Capital Management, LLC | 693789 | 1.20% | 25000 | 3.74% | 2018-06-30 |
| Capital Guardian Trust Company | 646009 | 1.12% | -15253 | -2.31% | 2018-06-30 |
| Baillie Gifford & Co Limited. | 626603 | 1.08% | 44462 | 7.64% | 2018-06-30 |
| Balyasny Asset Management LLC | 683364 | 1.19% | -446899 | -39.54% | 2018-03-31 |
| Polar Capital LLP | 631669 | 1.09% | 166669 | 35.84% | 2018-07-31 |
| Arrowpoint Asset Management, LLC | 571914 | 0.99% | 433546 | 313.33% | 2018-03-31 |
| Columbia Wanger Asset Management LLC | 760116 | 1.56% | -129026 | -14.51% | 2017-12-31 |
| Capital World Investors | 663000 | 1.36% | -- | -- | 2017-12-31 |
| Deutsche Asset & Wealth Management Investment GmbH | 392368 | 0.68% | -265 | -0.07% | 2018-05-17 |
| Goldman Sachs Asset Management LP | 537842 | 1.10% | -59282 | -9.93% | 2017-12-31 |
| Flagship Ventures 2007 General Partner LLC | 965369 | 2.29% | -965000 | -49.99% | 2016-12-31 |
| Vanguard Specialized Funds | 3874924 | 7.94% | 293290 | 8.19% | 2017-12-31 |
| Redmile Group, LLC | 737900 | 1.76% | 737900 | -- | 2016-09-30 |
| Artal Group S A | 400000 | 0.95% | 25000 | 6.67% | 2016-09-30 |
| BlackRock Advisors LLC | 385747 | 0.92% | 132724 | 52.46% | 2016-09-30 |
| Wellington Management Group LLP | 2014480 | 3.00% | 189965464 | -- | 1999-11-30 |
| ARCH Venture Fund VII, L.P. | 3088590 | 3.00% | 291254037 | 0.10% | 1999-11-30 |
| Robert T. Nelsen | 3093050 | 3.00% | 291674615 | 0.10% | 1999-11-30 |
| Entities affiliated with Celgene Corporation | 5242704 | 3.00% | 494386987 | 0.10% | 1999-11-30 |
| Entities affiliated with Fidelity Management& Research Company | 5494348 | 3.00% | 518117016 | 0.20% | 1999-11-30 |
| 共同基金持股 | |||||
|---|---|---|---|---|---|
| 持有者 | 持有份额 | 持股比例 | 份额变化 | 变化率 | 报告日期 |
| Fidelity Advisor | 512743 | 0.87% | -- | -- | 2019-06-30 |
| Vanguard Health Care Fund | 4402124 | 7.49% | -- | -- | 2019-03-31 |
| Fidelity Growth Company Commingled Pool | 2284101 | 3.89% | 103554 | 4.75% | 2019-06-30 |
| American Funds New Perspective Fund | 2086622 | 3.55% | -- | -- | 2019-06-30 |
| First Trust NYSE Arca Biotech Fund | 2018072 | 3.43% | -4863 | -0.24% | 2019-07-31 |
| Vanguard Total Stock Market Index Fund | 1427601 | 2.43% | 245 | 0.02% | 2019-06-30 |
| Vanguard Small Cap Index | 1272506 | 2.17% | -23420 | -1.81% | 2019-06-30 |
| SPDR | 1031395 | 1.76% | 20235 | 2.00% | 2019-07-31 |
| ClearBridge Aggressive Growth Fund | 1021242 | 1.74% | -15000 | -1.45% | 2019-06-30 |
| Columbia Acorn Fund | 883362 | 1.50% | -87000 | -8.97% | 2019-06-30 |
| iShares Nasdaq Biotechnology ETF | 579574 | 0.99% | 6016 | 1.05% | 2019-07-30 |
| T. Rowe Price Health Sciences Fund | 596416 | 1.02% | -109600 | -15.52% | 2019-06-30 |
| American Funds IS | 612920 | 1.04% | -- | -- | 2019-06-30 |
| T. Rowe Price New Horizons Fund | 675031 | 1.15% | -5400 | -0.79% | 2019-06-30 |
| Vanguard Extended Market Index Fund | 704777 | 1.20% | -209 | -0.03% | 2019-06-30 |
| Vanguard Small Cap Growth Index Fund | 731216 | 1.24% | -2404 | -0.33% | 2019-06-30 |
| Fidelity | 782733 | 1.33% | -- | -- | 2019-06-30 |
| Hartford MidCap Fund | 1213494 | 2.07% | -449478 | -27.03% | 2019-04-30 |
| DWS Verm | 942008 | 1.60% | 706506 | 300.00% | 2019-04-30 |
| Vanguard Small Cap Index Fund | 1297501 | 2.21% | 8930 | 0.69% | 2019-04-30 |
| VA CollegeAmerica New Perspective Fd | 2086622 | 3.57% | -- | -- | 2018-12-31 |
| Polar Capital Healthcare Opps Fund | 427342 | 0.73% | 200 | 0.05% | 2018-09-30 |
| VA CollegeAmerica Smcap World 529E | 420000 | 0.72% | -- | -- | 2018-06-30 |
| Vanguard Health Care Inv | 4233424 | 7.31% | -119700 | -2.75% | 2018-06-30 |
| VA CollegeAmerica New Perspective 529E | 2086622 | 3.60% | -- | -- | 2018-06-30 |
| Hartford MidCap A | 1532864 | 2.64% | 48574 | 3.27% | 2018-07-31 |
| Vanguard Total Stock Mkt Idx | 1231153 | 2.12% | 8852 | 0.72% | 2018-07-31 |
| ClearBridge Aggressive Growth A | 1036242 | 1.79% | -- | -- | 2018-07-31 |
| T. Rowe Price Health Sciences | 839455 | 1.45% | -98432 | -10.50% | 2018-06-30 |
| T. Rowe Price New Horizons | 801955 | 1.38% | -103100 | -11.39% | 2018-06-30 |
| iShares Nasdaq Biotechnology | 654001 | 1.04% | -1245 | -0.19% | 2018-09-12 |
| American Funds NVIT Growth-Income II | 612920 | 1.06% | -26580 | -4.16% | 2018-06-30 |
| Vanguard Extended Market Idx Inv | 656059 | 1.13% | 6 | -- | 2018-07-31 |
| Vanguard Small Cap Growth Index Inv | 701798 | 1.21% | 8962 | 1.29% | 2018-07-31 |
| First Trust NYSE Arca Biotech ETF | 816091 | 1.30% | -- | -- | 2018-09-13 |
| Columbia Acorn Z | 491259 | 1.01% | -- | -- | 2017-12-31 |
| Fidelity® Contrafund® Fund | 1308987 | 3.50% | -602 | -- | 2015-09-30 |
| American Funds NVIT Growth | 1292120 | 3.40% | -17000 | -1.30% | 2015-09-30 |
| Fidelity Advisor® New Insights Fund | 846562 | 2.20% | -- | -- | 2015-09-30 |
| VA CollegeAmerica Small Cap World | 488000 | 1.30% | -123000 | -20.10% | 2015-09-30 |
| Fidelity® Series Growth Company Fund | 392766 | 1.00% | -- | -- | 2015-09-30 |
| American Funds NVIT Growth-Income Fund | 378000 | 1.00% | -- | -- | 2015-09-30 |
| Fidelity® Growth Company Fund | 1453808 | 3.90% | -15900 | -1.10% | 2015-09-30 |
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